@import url("https://fonts.googleapis.com/css?family=Lato:400,700,700i&display=swap");
@import url("https://fonts.googleapis.com/css2?family=Lato:ital,wght@0,900;1,400&display=swap");

:root {
  --primary-color: #288aab;
}

body {
  font-family: "Lato";
  font-size: 14px;
  color: #24292c;
}

h1,
.h1,
h2,
.h2,
h3,
.h3,
h4,
.h4,
h5,
.h5,
h6,
.h6 {
  font-weight: 700;
  line-height: 1;
  color: #24292c;
  margin-top: 0;
}

h1 {
  font-size: 40px;
  line-height: 45px;
  padding-bottom: 20px;
}

h2 {
  font-size: 23px;
  line-height: 28px;
}

h3 {
  font-size: 20px;
  line-height: 25px;
}

p {
  margin: 0 0 20px;
}

a {
  color: var(--primary-color);
}

a:visited {
  color: #288aab;
  text-decoration: none;
}

a:hover,
a:focus {
  color: #00ced8;
  text-decoration: none;
}

.mtb30 {
  margin-bottom: 30px !important;
  margin-top: 30px !important;
}
.mb20 {
  margin-bottom: 20px !important;
}
.mb10 {
  margin-bottom: 0px !important;
}
.mb0 {
  margin-bottom: 0px !important;
}
.mb5 {
  margin-bottom: 5px !important;
}
.mb40 {
  margin-bottom: 40px !important;
}
.mt20 {
  margin-top: 20px !important;
}

#Contact-us .pull-right img {
  padding-top: 5px;
}

p {
  font-size: 16px;
}
.p20 {
  font-size: 20px;
}
.fz25 {
  font-size: 25px;
}
.fz28 {
  font-size: 28px;
  line-height: 1.234;
}
.fz32 {
  font-size: 32px;
}
.primary-text-color {
  color: var(--primary-color);
}

.fa-check-circle {
  color: #95d82c;
}

.inline {
  display: inline;
  padding-right: 15px;
}
.center-margin {
  margin: 0 auto;
}

.mb5 {
  margin-bottom: 5px;
}

.contact-us a:visited,
.contact-us a:focus {
  text-decoration: none;
  color: #288aab;
}

.contact-us a:hover {
  text-decoration: none;
  color: #00ced8;
}

.codebreakbtn {
  background-color: transparent;
  color: #288aab;
  font-size: 20px;
  border: 1px solid #00ced8;
  margin: 10px 0;
  -webkit-transition: all 1s;
  transition: all 1s;
}
.trial-status .codebreakbtn {
  margin: 0;
}

.trial-status .col-sm-1 {
  padding-right: 10px;
}
#Purpose .codebreakbtn {
  font-size: 16px;
}

.codebreakbtn.white {
  background-color: #ffffff;
  margin-right: 20px;
}
.codebreakbtn:hover,
.codebreakbtn.white:hover,
.printbtn:hover {
  background-color: rgba(22, 122, 157, 0.1);
  color: #288aab;
  -webkit-transition: all 1s;
  transition: all 1s;
}

.main-menu.navbar-inverse {
  background-color: #f2f8fa; /* #288AAB0F */
  border: 0;
  border-radius: 0px;
  position: fixed;
  width: 100%;
  margin: 0 auto;
  top: 40px;
  z-index: 10;
}
.trials .main-menu.navbar-inverse {
  position: absolute;
}

.upper-block {
  padding-bottom: 10px;
  position: fixed;
  width: 100%;
  margin: 0 auto;
  z-index: 10;
  background-color: #ffffff;
}

.trials .upper-block {
  position: absolute;
}

.row.eligibility {
  padding-top: 30px;
}

#PageStarts {
  padding-top: 135px;
}

#trails {
  border-top: 7px solid #95d82c;
  margin-top: -9px;
}

.code-break-trail-101 {
  border-top: 0px solid #00ced8 !important;
  margin-top: -9px;
}
.navbar {
  min-height: 81px;
  margin-bottom: 0px;
}

.topmenu.nav > li > a {
  padding: 10px 20px 0px 20px;
  color: #24292c;
}

.topmenu.nav > li > a > span:before {
  content: " ";
  background-image: url(../images/magnifying-glass-icon.png);
  width: 16px;
  height: 18px;
  position: absolute;
  left: 0px;
  top: 12px;
}
.topmenu.nav > li:last-child > a > span:before {
  content: " ";
  background-image: url(../images/mail-icon.png);
  width: 14px;
  height: 14px;
  position: absolute;
  left: 0px;
  top: 14px;
}
.topmenu.nav > li:hover > a > span:before {
  background-image: url(../images/magnifying-glass-icon-hover.png);
}
.topmenu.nav > li:last-child:hover > a > span:before {
  background-image: url(../images/mail-icon-hover.png);
}

.navbar-inverse .navbar-nav > li > a {
  color: #24292c;
}

.topmenu.nav > li > a:focus,
.topmenu.nav > li > a:hover {
  background-color: transparent;
  color: #00ced8;
}

.main-menu .navbar {
  min-height: 95px;
  margin-bottom: 0px;
}

.main-menu .nav > li > a {
  position: relative;
  display: block;
  padding: 0 0 21px 0;
  font-size: 16px;
}

.main-menu.navbar-inverse .navbar-nav > li:focus > a,
.main-menu.navbar-inverse .navbar-nav > li:hover > a {
  border-bottom: 0px solid #00ced8;
  opacity: 1;
}
.main-menu.navbar-inverse .navbar-nav > li > a,
.main-menu.navbar-inverse .navbar-nav > li > a {
  margin-bottom: 9px;
}
.main-menu.navbar-inverse .navbar-nav > li.active > a,
.main-menu.navbar-inverse .navbar-nav > li.active > a {
  border-bottom: 9px solid #00ced8;
  opacity: 1;
  color: inherit;
  background-color: inherit;
  margin-bottom: 0px;
}

.main-menu.navbar-inverse .navbar-nav > li > a:focus,
.main-menu.navbar-inverse .navbar-nav > li > a:hover {
  color: #00ced8;
}

.main-menu.navbar-inverse .navbar-nav > li.active > a:hover,
.main-menu.navbar-inverse .navbar-nav > li.active > a:focus {
  border-bottom: 9px solid #00ced8;
  opacity: 1;
  color: #00ced8;
  background-color: inherit;
}

.main-menu.navbar-inverse .navbar-nav > .open > a,
.main-menu.navbar-inverse .navbar-nav > .open > a:focus,
.main-menu.navbar-inverse .navbar-nav > .open > a:hover {
  color: #00CED8;
  background-color: transparent;
}

.trial-status {
  border: 1px solid #00ced8;
  padding: 30px 20px 25px;
  background-color: #ffffff;
  margin-bottom: 25px;
}
.trial-status.first {
  margin-top: 35px;
}
.trials .trial-status {
  border: 0px solid #00ced8;
  padding: 30px 0px 5px;
  /* display: flex;
    align-items: center; */
}

.trial-status h3 {
  line-height: 25px;
}

.trial-status .heading {
  font-size: 12px;
  text-transform: uppercase;
  color: #373a3c;
}

.contact-us {
  padding-top: 0px;
  padding-bottom: 15px;
  margin-top: 1px !important;
}
.trials .contact-us {
  padding-top: 10px;
  padding-bottom: 35px;
}

.trial-status .data {
  font-weight: bold;
  font-size: 15px;
}

.trial-status p {
  margin-bottom: 2px;
}

.nav-pills > li {
  padding: 15px 15px 0 15px;
}
.nav-pills > li > a {
  padding: 0 0 4px 0;
  border-radius: 0px;
}

.hero-image {
  height: auto;
  background-repeat: no-repeat;
  background-size: cover;
  position: relative;
  min-height: 650px;
}

.code-breaktext {
  position: absolute;
  /*top: 10%;*/
  right: 0;
  width: 56%;
  padding-bottom: 35px;
  padding-left: 25px;
  padding-top: 80px;
  background: #ffffff95 0% 0% no-repeat padding-box;
  background: rgba(255, 255, 255, 0.584);
  border: 1px solid #ffffff;
  border-radius: 10px;
}

.code-breaktext h2 {
  padding-bottom: 10px;
}
.code-breaktext img {
  padding-bottom: 20px;
}

.code-breaktext img {
  /* 	max-width: 510px; */
}

.code-breaktext h2 {
  font-size: 24px;
  letter-spacing: 0;
  font-weight: 400;
  line-height: 35px;
}
.code-breaktext h2 b {
  font-weight: 900;
  cursor: context-menu;
}
.blue-green-color {
  color: #2889aa;
}
.code-breaktext h2 .blue-green-color:hover {
  color: #00ced8;
}

.hero-image .codebreakbtn-home {
  padding: 10px 35px;
  margin: 15px 0 20px 0;
}

*:focus {
  outline: 0 !important;
}

.explore-heading {
  padding-top: 30px;
}

.grey-background {
  background-color: #f2f8fa;
}

.white-background {
  background-color: #fff;
}

.light-blue-background {
  background-color: #f2f8fa;
}
.mutation {
  border-radius: 10px;
  padding: 15px;
}

.roundsection {
  padding: 0px 0px 80px 0px;
}

.round74 {
  height: 74px;
  width: 74px;
  border-radius: 50%;
  background-color: #cccccc;
  margin: 0 auto;
}

.round113 {
  height: 113px;
  width: 113px;
  border-radius: 50%;
  background-color: #cccccc;
}

.round45 {
  height: 45px;
  width: 45px;
  border-radius: 50%;
  background-color: #cccccc;
}

.NSCLC-block {
  padding: 30px 35px;
}

.corner-radious {
  border-radius: 10px;
}

.knowKras12GMutation {
  background-color: #288aab;
  border-radius: 10px;
  color: #fff;
  padding: 20px;
}

.knowKras12GMutation p {
  margin-bottom: 0px;
}

.knowKras12GMutation a,
.knowKras12GMutation a:hover {
  color: #3ed9e0;
}

.knowKras12GMutation h2 {
  margin-top: 0px;
  color: #ffffff;
}

.img-center {
  margin: 0 auto;
}

.header-logo {
  width: 247px;
}

.NSCLCbtn {
  background-color: #707070;
  color: #fff;
}

.topbtnSec {
  position: relative;
}

.topbutton {
  position: fixed;
  opacity: 0;
  width: 50px;
  height: 50px;
  background-color: rgba(40, 138, 171, 0.533);
  bottom: 170px;
  right: 20px;
  transition: all 0.4s linear;
}
.topbutton.show {
  opacity: 1;
  transition: all 0.4s linear;
}

.topbutton:hover {
  transform: scale(1.1);
  transition: all 0.4s;
}

.arrowbtn {
  position: absolute;
  left: 15px;
  top: 15px;
  font-size: 30px;
  color: #fff;
}

.removetopmargin {
  margin-top: 0px;
}

.second-menu {
  border-top: 1px solid #00ced8;
  border-bottom: 1px solid #00ced8;
}

.second-menu .nav > li > a:focus,
.second-menu .nav > li > a:hover {
  text-decoration: none;
  background-color: transparent;
}
.second-menu .nav > li > a:hover {
  color: #00ced8;
}

.second-menu .nav-pills {
  float: left;
}

.second-menu .nav-pills > li > a {
  color: #000;
  font-size: 16px;
}

.second-menu .nav-pills > li.active > a {
  border-bottom: 8px solid #95d82c;
}
.codebreak-101 .second-menu .nav-pills > li.active > a {
  border-bottom: 8px solid #00ced8 !important;
}
.second-menu .nav-pills > li:hover > a {
  border-bottom: 8px solid #95d82c;
  color: #95d82c;
}
.codebreak-101 .second-menu .nav-pills > li:hover > a {
  border-bottom: 8px solid #00ced8;
  color: #00ced8;
}
.second-menu .nav-pills > li.active > a,
.second-menu .nav-pills > li.active > a:focus,
.second-menu .nav-pills > li.active > a:hover {
  color: #000;
  background-color: transparent;
}
.dropdown-menu > li > a:focus,
.dropdown-menu > li > a:hover {
  background-color: unset;
}

.printbtn {
  background-color: transparent;
  border: 1px solid #00ced8;
  margin-top: 6px;
  margin-bottom: 6.5px;
  color: #56a3bd;
  font-size: 20px;
}
.second-menu .printbtn {
  font-size: 16px;
}
.second-menu .printbtn .fa {
  font-weight: 700;
  font-size: 120%;
  padding-right: 5px;
}
.trials #Purpose .mutation {
  background: #ffffff 0% 0% no-repeat padding-box;
  border: 2px solid #95d82c;
  border-radius: 8px;
  float: right;
  max-width: 450px;
}
.trials #Purpose .mutation a:hover {
  color: inherit;
  text-decoration: none;
}
.trials #Purpose .mutation .f32 {
  color: #288aab;
  font-size: 32px;
  padding-bottom: 15px;
}
.trials #Purpose .mutation h3 {
  color: #288aab;
}
.codebreak200btn {
  background-color: #707070;
  color: #fff;
  font-size: 18px;
  padding: 15px 10px;
}

.roundheadingmargin {
  margin-top: 20px;
}

.section {
  padding: 50px 0px 5px 0px;
}
#Purpose .section {
  padding: 40px 0px 35px 0px;
}
#Study-Drugs .section {
  padding: 60px 0px 65px 0px;
}
#Overview .section {
  padding: 60px 0px 0px 0px;
}
.nlp {
  padding-left: 0;
}
.nrp {
  padding-left: 0;
}
#Overview .right-block {
  padding-top: 50px;
}
.centercontainer {
  display: flex;
  align-items: center;
  justify-content: center;
}

.codebreak200Text {
  margin-top: 0px;
}

.for-moreInfo {
  padding-left: 15px;
}

.right-trailsection {
  margin-top: 20px;
}

.participate-sub-block {
  border: 2px solid #95d82c;
  border-radius: 10px;
  padding: 20px;
  margin-top: 10px;
  margin-bottom: 10px;
}
.border-color-101 {
  border: 2px solid #00ced8 !important;
}
.participate-sub-block p {
  margin-bottom: 0;
}

.panel-heading {
  padding: 0;
  border: 0;
}

.panel-title > a,
.panel-title > a:active {
  display: block;
  padding: 15px;
  color: #555;
  letter-spacing: 0px;
  word-spacing: 0px;
  text-decoration: none;
}

.panel-default > .panel-heading {
  background-color: #fff;
}

.panel-heading a:before {
  font-family: "Glyphicons Halflings";
  content: "\e114";
  float: right;
  transition: all 0.5s;
  font-size: 10px;
}

.panel-heading.active {
  background-color: #f2f8fa;
}

.panel-heading.active a:before {
  -webkit-transform: rotate(180deg);
  -moz-transform: rotate(180deg);
  transform: rotate(180deg);
}

.panel-group .panel-heading + .panel-collapse > .list-group,
.panel-group .panel-heading + .panel-collapse > .panel-body {
  border-top: 0px solid #ddd;
  font-size: 16px;
}

#accordion a:focus,
#accordion a:hover {
  color: #555555;
}

.panel-group .panel {
  background-color: #f2f8fa;
  border-radius: 0px;
  margin-bottom: 15px;
}

.panel-heading {
  border-top-left-radius: 0px;
  border-top-right-radius: 0px;
}

.navbar-nav > li > .dropdown-menu {
  border: none;
  margin-top: 10px;
}

.blue-background {
  background-color: #288aab;
}

.white-color {
  color: #fff;
}

.green-text {
  color: #69adc4;
}

ul.trailul {
  padding-left: 20px;
  margin-bottom: 0px;
  padding-bottom: 15px;
}

sub {
  font-size: 14px;
}

.panel {
  border: 1px solid #00ced8;
}

.panel-title > a,
.panel-title > a:active {
  color: #288aab;
}

.panel-title > a:hover {
  background-color: #f2f8fa;
  color: #288aab;
  -webkit-transition: all 1s;
  transition: all 1s;
}

#accordion a:focus,
#accordion a:hover {
  color: #288aab;
}

.modal-timings {
  padding-left: 15px;
}

.modal-dialog {
  /* padding-top: 10%; */
}

textarea {
    padding: 8px;
    margin: 0px 0px 8px 0px;
    border: 1px solid #dddddd;
	margin-bottom: 1.5rem;
}
.plmt-adjust {
    padding-left: 16px;
    /* margin-top: -19px; */
    margin-bottom: 0;
    font-size: 16px;
}
.pl-adjust {
    padding-left: 18px;
}

.submit-btn {
    width: 99px;
    height: 35px;
    border-radius: 4px;
    background-color: #ffffff;
    border: 1px solid #00ced8;
    padding: 0px;
    /* margin-left: -13px; */
}

.error {
    color: red;
    display: inline-block;
}

.modal-header {
  background-color: #288aab;
  padding: 20px 12px 20px 20px;
}

.modal-header h2 {
  color: #fff;
}

.modal-header .close .video-modal-close {
  margin-top: -6px;
  font-size: 38px;
}

.modal-body {
  background-color: #fff;
  padding: 20px;
}
.modal-body p:last-child {
  margin-bottom: 0;
}

.modal-content {
  background-color: transparent;
}

.close,
.video-modal-close .close:hover {
  color: #fff;
  opacity: 1;
}
.panel-title {
  line-height: 20px;
}
.f32 {
  color: #95d82c;
}
.info-right {
  margin-top: 10px;
}
.info-left-img {
  margin-top: 15px;
}
.blecolored-text {
  color: #288aab;
}
footer {
  background-color: #288aab;
  padding-bottom: 10px;
  padding-top: 20px;
}
.trials footer {
  border-top: 7px solid #00ced8;
}

.codebreak-101 footer {
  border-top: 7px solid #00ced8 !important;
}
footer a,
footer a:hover,
footer a:visited,
footer p {
  color: #fff;
  text-decoration: none;
  font-size: 14px;
}
footer a:hover {
  text-decoration: none;
  color: #00ced8;
}
footer a:focus {
  text-decoration: none;
  color: #fff;
}
.trial-status-img {
  width: 100%;
}
.sticky {
  position: fixed;
  top: 0px;
  width: 100%;
  background-color: #fff;
  z-index: 2;
}

.sticky + .toolkit-page-background {
  padding-top: 102px;
}

.trials.codebreak-101 #Purpose .mutation .f32:hover {
  color: #00ced8;
}
.trials.codebreak-200 #Purpose .mutation .f32:hover {
  color: #95d82c;
}
.clinical-trial-period {
  position: relative;
}
.clinical-trial-period img {
  position: absolute;
  top: 20px;
  left: 0;
  right: 0;
}
/* .screening-period{
		top:15px;
	}
	.treatment-period{
		top:200px;
	}
	.follow-up-period{
		top:390px;
	} */

.line {
  transform: rotate(90deg);
  width: 416px;
  left: -110px;
  position: absolute;
  top: 219px;
  border-top: 2px solid #eee;
}

.modal-backdrop.fade.menu {
  display: none;
}

#hcpmodal .modal-body {
  padding-bottom: 0px;
}
.button-close {
  padding: 10px 25px !important;
}
@media (min-width: 768px) {
	.borderbottom {
		border-bottom: 1px solid #000;
	}
  .navbar-nav.amgen-logo > li > a {
    padding-top: 10px;
    padding-left: 5px;
  }
  .navbar-nav.amgen-logo > li > a:hover,
  .navbar-nav.amgen-logo > li > a:active {
    padding-top: 10px;
    background-color: inherit;
  }
  .main-menu .navbar {
    border-radius: 0px;
  }

  .home-page .hero-image {
    background-image: url(../images/hero-image-home.png);
  }

  .main-menu .navbar-nav > li {
    padding: 36px 35px 0 0;
  }
  .main-menu .navbar-nav > li:nth-last-of-type(1) {
    padding-right: 0;
  }

  .navbar-right .dropdown-menu {
    right: auto;
    width: 304px;
  }

  .trial-status .row:first-child {
    padding-bottom: 15px;
  }
  .printbtndiv {
    text-align: right;
  }

  p.nmb {
    margin-bottom: 0;
  }
  h3.nmb {
    margin-bottom: 0;
  }
  .roundsection .img-container {
    min-height: 140px;
  }
  .roundsection .text-container {
    min-height: 140px;
  }
  .roundsection .row div {
    display: flex;
    align-items: center;
    justify-content: center;
  }

  footer a {
    padding-top: 10px;
    float: left;
  }

  footer p {
    padding-top: 20px;
  }
  .cpwttext {
    padding-top: 0px;
  }

  .footertext {
    float: left;
    padding-left: 20px;
  }

  .footer-logo {
    margin-top: 20px;
    margin-bottom: -5px;
  }

  .footer-link {
    padding-right: 20px;
    padding-left: 0px;
    padding-top: 20px;
  }
  .footnote-insidebox {
	padding-left: 20px;
    line-height: 1;
    padding-bottom: 10px;
	margin-bottom: 0;
  }
}

@media (min-width: 992px) and (max-width: 1199px) {
  .code-breaktext {
    width: 45%;
  }
  .code-breaktext h2 {
    font-size: 20px;
    line-height: 30px;
  }
  .line {
    left: -125px;
  }
}
@media (min-width: 851px) and (max-width: 991px) {
  .code-breaktext {
    width: 45%;
    padding-bottom: 20px;
    padding-left: 20px;
    padding-top: 50px;
  }
  .code-breaktext h2 {
    font-size: 18px;
    line-height: 25px;
  }
  .hero-image .codebreakbtn-home {
    padding: 10px 15px;
    margin: 15px 0 10px 0;
  }
  .home-page .hero-image {
    min-height: 515px;
  }
  .code-breaktext h2 {
    padding-bottom: 5px;
  }
  .code-breaktext img {
    padding-bottom: 15px;
  }
}
@media (min-width: 768px) and (max-width: 850px) {
  .code-breaktext {
    width: 45%;
    padding-bottom: 20px;
    padding-left: 20px;
    padding-top: 50px;
  }
  .code-breaktext h2 {
    font-size: 18px;
    line-height: 25px;
  }
  .hero-image .codebreakbtn-home {
    padding: 10px 15px;
    margin: 15px 0 10px 0;
  }
  .home-page .hero-image {
    min-height: 515px;
  }
  .code-breaktext h2 {
    padding-bottom: 5px;
  }
  .code-breaktext img {
    padding-bottom: 15px;
  }
}

@media (max-width: 1024px) {
  footer p {
    padding-top: 20px;
    font-size: 12px;
  }
  /* .follow-up-period{
		top:375px;
	} */
  .line {
    width: 386px;
    left: -132px;
    top: 200px;
  }
}

@media (max-width: 991px) {
  .main-menu .nav > li > a {
    /*  padding: 25px 20px;   */
  }

  .main-menu .navbar-nav > li {
    padding: 0px;
    margin-top: -44px;
    padding: 30px 0px 0px 40px;
  }

  .footertext {
    font-size: 11px;
  }

  .footer-link {
    /*padding-right: 0px;*/
  }

  .second-menu .nav-pills > li > a {
    font-size: 15px;
  }

  .second-menu .nav-pills > li.active {
    /*border-bottom: 11px solid #00CED8;*/
  }

  .printbtn {
    margin-top: 6px;
  }
  .trial-status-img {
    width: 100%;
  }

  .codebreakbtn-home {
    padding: 10px 10px;
    font-size: 15px;
    /* width: 100%; */
  }
  .line {
    top: 245px;
    left: -130px;
  }

  /* .treatment-period {
		top: 225px;
	}
	.follow-up-period {
		top: 416px;
	} */
  .nav-pills > li {
    padding: 15px 12px 0 15px;
  }
}
@media (min-width: 768px) and (max-width: 990px) {
  .navbar-toggle {
    display: inline-block;
  }
  .navbar-toggle.collapsed {
    margin-top: 10px;
    z-index: 1111;
    position: absolute;
    top: 0px;
    right: 0px;
  }
  .navbar-inverse .navbar-toggle,
  .navbar-inverse .navbar-toggle:hover,
  .navbar-inverse .navbar-toggle:focus {
    border-color: transparent;
    background-color: transparent;
    z-index: 1111;
  }
  .navbar-toggle.collapsed .icon-bar {
    display: block;
    width: 28px;
    height: 2px;
    border-radius: 1px;
  }
  .navbar-toggle .icon-bar + .icon-bar {
    margin-top: 6px;
  }
  .navbar-inverse .navbar-toggle .icon-bar {
    background-color: #24292c;
  }
  .navbar-toggle.collapsed .top-bar {
    transform: rotate(0);
  }
  .navbar-toggle .icon-bar {
    display: block;
    width: 28px;
    height: 2px;
    border-radius: 1px;
    margin-top: 10px;
  }
  .navbar-toggle .top-bar {
    transform: rotate(45deg);
    transform-origin: 10% 10%;
  }
  .navbar-toggle .middle-bar {
    opacity: 0;
  }
  .navbar-toggle.collapsed .middle-bar {
    opacity: 1;
  }
  .navbar-toggle .bottom-bar {
    transform: rotate(-45deg);
    transform-origin: 10% 90%;
  }
  .navbar-toggle.collapsed .bottom-bar {
    transform: rotate(0);
  }
  .navbar-nav:last-child {
    float: right;
  }
  .container-fluid > .navbar-collapse,
  .container-fluid > .navbar-header,
  .container > .navbar-collapse,
  .container > .navbar-header {
    margin-right: 0;
    margin-left: 0;
  }
  .container-fluid > .navbar-collapse,
  .container-fluid > .navbar-header,
  .container > .navbar-collapse,
  .container > .navbar-header {
    margin-left: 0px;
  }
  .in .navbar-nav {
    margin: 0 auto;
    float: left !important;
    padding-top: 10px;
  }
  .navbar-nav {
    margin: 0 auto;
    float: left;
  }
  .navbar-collapse.collapse.in {
    background-color: #fff;
    left: 0%;
    margin: 0;
    transition: all 0.6s ease;
    height: 812px !important;
    /* border-left: 19px solid #8C8F90; */
    margin-left: 50%;
    position: absolute;
    top: -42px;
    width: 50%;
    z-index: 1100;
  }
  .navbar-collapse {
    position: absolute;
    height: auto !important;
    left: 100vw;
    background-color: #f2f8fa;
    width: 100%;
    transition: all 0.6s ease;
  }
  .topmenu li:last-child a {
    padding-right: 0;
  }
  .navbar-toggle {
    margin-top: 10px;
    z-index: 100;
    position: absolute;
    top: -50px;
    right: -10px;
  }
  .main-menu .navbar-nav > li {
    padding: 0px;
    margin-top: 17px;
  }
  .nav > li {
    position: relative;
    display: block;
  }
  .main-menu.navbar-inverse .navbar-nav > li.active > a,
  .main-menu.navbar-inverse .navbar-nav > li.active > a {
    border-bottom: 0px solid #00ced8;
  }
  .navbar-nav > li {
    float: none;
  }
  .topmenu.navbar-nav > li {
    float: left;
  }
  #trails {
    border-top: 7px solid #95d82c;
    margin-top: 0px;
  }
  #PageStarts {
    padding-top: 120px;
  }
  .code-breaktext img {
    padding-bottom: 15px;
    max-width: 266px;
  }
  .code-breaktext h2 {
    font-size: 16px;
    line-height: 25px;
  }
  h1 {
    font-size: 30px;
    line-height: 35px;
    padding-bottom: 10px;
  }
  .p20 {
    font-size: 16px;
  }
  .mtb30 {
    margin-bottom: 10px !important;
    margin-top: 10px !important;
  }
  .trial-status h3 {
    line-height: 20px;
    font-size: 16px;
  }
  .trial-status .heading {
    font-size: 10px;
  }
  .trial-status .data {
    font-weight: bold;
    font-size: 13px;
  }
  .trial-status .row:first-child {
    padding-bottom: 10px;
  }
  .codebreakbtn-home {
    padding: 5px 10px;
  }
  footer a,
  footer a:hover,
  footer a:visited,
  footer p {
    color: #fff;
    text-decoration: none;
    font-size: 12px;
  }
  .fz32 {
    font-size: 20px;
    line-height: 25px;
  }
  .trials .trial-status {
    margin-bottom: 5px;
  }
  h3 {
    font-size: 18px;
    line-height: 25px;
  }
  #second-menu .desktop-only {
    display: none;
  }
  #second-menu .mobile-only {
    display: block;
  }
  .mobiledropdown,
  .mobiledropdown.active.focus,
  .mobiledropdown.active:focus,
  .mobiledropdown.active:hover,
  .mobiledropdown:active.focus,
  .mobiledropdown:active:focus,
  .mobiledropdown:active:hover,
  .open > .dropdown-toggle.mobiledropdown.focus,
  .open > .dropdown-toggle.mobiledropdown:focus,
  .open > .dropdown-toggle.mobiledropdown:hover {
    width: 100%;
    border-radius: 0px;
    background-color: #fff;
    color: #000;
    border: 10px solid #95d82c;
    border-left: 40px solid #95d82c;
    border-right: 40px solid #95d82c;
    text-align: left;
    font-size: 14px;
    line-height: 14px;
  }
  .codebreak-101 .mobiledropdown,
  .mobiledropdown.active.focus,
  .mobiledropdown.active:focus,
  .mobiledropdown.active:hover,
  .mobiledropdown:active.focus,
  .mobiledropdown:active:focus,
  .mobiledropdown:active:hover,
  .open > .dropdown-toggle.mobiledropdown.focus,
  .open > .dropdown-toggle.mobiledropdown:focus,
  .open > .dropdown-toggle.mobiledropdown:hover {
    width: 100%;
    border-radius: 0px;
    background-color: #fff;
    color: #000;
    border: 10px solid #00ced8;
    border-left: 40px solid #00ced8;
    border-right: 40px solid #00ced8;
    text-align: left;
    font-size: 14px;
    line-height: 14px;
  }
  .main-menu.navbar-inverse .navbar-nav > li.active > a:hover,
  .main-menu.navbar-inverse .navbar-nav > li.active > a:focus {
    border-bottom: 0px solid #00ced8;
  }
  .navbar-inverse .navbar-toggle:focus,
  .navbar-inverse .navbar-toggle:hover {
    background-color: transparent;
  }
  .dropdown-menu {
    width: 100%;
  }
  .second-menu {
    border-top: 0px solid #00ced8;
    border-bottom: 0px solid #00ced8;
  }
  .second-menu .container {
    width: 100%;
  }
  .mobiledropdown:before {
    font-family: "Glyphicons Halflings";
    content: "\e114";
    float: right;
    transition: all 0.5s;
    font-size: 10px;
    padding-top: 0px;
    color: #69adc4;
  }
  .navbar {
    min-height: 80px;
  }
  .main-menu.navbar-inverse {
    height: 60px;
  }
  .trials .navbar-collapse.collapse {
    display: none !important;
  }
  .trials .navbar-collapse.collapse.in {
    display: block !important;
  }
  .fz28 {
    font-size: 22px;
  }
  h2 {
    font-size: 16px;
    line-height: 16px;
  }
  #Contact-us {
    padding-bottom: 15px;
  }
  .panel-body {
    padding: 10px 15px 15px 15px;
  }
}

@media (max-width: 767px) {
  #trails {
    margin-top: 30px;
  }
  .padding-right {
    padding-right: 0 !important;
  }
  .dropdown-menu > li > a {
    font-size: 14px !important;
    background-color: #ffffff !important;
  }
  .main-menu.navbar-inverse {
    height: 60px;
  }
  .topmenu.nav > li > a > span:before {
    width: 12px;
    background-size: contain;
    height: 13px;
    left: -3px;
    top: 15px;
  }
  .topmenu.nav > li:last-child > a > span:before {
    background-size: contain;
    width: 11px;
    height: 11px;
    left: -3px;
    top: 15.5px;
  }
  .navbar-toggle .top-bar {
    transform: rotate(45deg);
    transform-origin: 10% 10%;
  }
  .navbar-toggle .bottom-bar {
    transform: rotate(-45deg);
    transform-origin: 10% 90%;
  }

  .navbar-toggle .middle-bar {
    opacity: 0;
  }

  .navbar-toggle.collapsed .top-bar {
    transform: rotate(0);
  }

  .navbar-toggle.collapsed .middle-bar {
    opacity: 1;
  }

  .navbar-toggle.collapsed .bottom-bar {
    transform: rotate(0);
  }

  .navbar-collapse {
    position: absolute;
    height: auto !important;

    left: 100vw;
    background-color: #f2f8fa;
    width: 100%;
    transition: all 0.6s ease;
  }
  .navbar-collapse.collapse.in {
    background-color: #fff;
    left: 0%;
    margin: 0;
    transition: all 0.6s ease;
    height: 812px !important;
    /* border-left: 19px solid #8C8F90; */
    margin-left: 20px;
    position: absolute;
    top: -42px;
    width: calc(100% - 20px);
    z-index: 1100;
  }
  .navbar-collapse.show {
    left: 0;
  }
  .second-menu {
    border-top: 0px solid #00ced8;
    border-bottom: 0px solid #00ced8;
  }

  /* .navbar-collapse{
		position: absolute;
		right:-800px;
		margin: 0 0 0 0;
		background-color:blue; 
		
		
	}
	*/
  .main-menu .navbar-nav > li {
    padding: 0px;
    margin-top: 17px;
  }
  .main-menu.navbar-inverse .navbar-nav > li.active > a:hover,
  .main-menu.navbar-inverse .navbar-nav > li.active > a:focus {
    border-bottom: 0px solid #00ced8;
  }
  .container-fluid > .navbar-collapse,
  .container-fluid > .navbar-header,
  .container > .navbar-collapse,
  .container > .navbar-header {
    margin-left: 0px;
  }

  .navbar-toggle {
    border: none;
    background: transparent !important;
  }

  .icon-bar {
    width: 22px;
    height: 2px;
    background-color: #b6b6b6;
    display: block;
    transition: all 0.2s;
    margin-top: 4px;
  }

  .trial-status-img {
    width: 70%;
  }

  h1 {
    font-size: 20px;
    line-height: 25px;
    padding-bottom: 0px;
    margin-bottom: 0;
  }

  h2 {
    font-size: 16px;
    line-height: 23px;
  }

  h3 {
    font-size: 16px;
    line-height: 20px;
  }
  p {
    font-size: 14px;
    margin: 0 0 5px;
  }
  img {
    max-width: 100%;
  }
  .row div[class^="col-sm"],
  .row div[class^="col-md"] {
    padding-top: 12px;
    padding-bottom: 12px;
  }
  .trial-status .row div[class^="col-sm"],
  .trial-status .row div[class^="col-md"] {
    padding-top: 10px;
    padding-bottom: 0px;
  }
  .trial-status .row div:last-child {
    padding-top: 15px;
    padding-bottom: 0px;
  }
  .trial-status .row div.col-sm-7 {
    padding-bottom: 5px;
  }
  .row.np-mobile div[class^="col-sm"],
  .row div[class^="col-md"] {
    padding-bottom: 0px;
  }
  .blank {
    padding: 0 !important;
  }
  .p20 {
    font-size: 14px;
  }
  .fz25 {
    font-size: 20px;
  }
  .fz28 {
    font-size: 20px;
  }
  .fz32 {
    font-size: 20px;
    text-align: left;
    margin-top: 20px;
  }
  .trials .trial-status {
    padding: 10px 0px 5px;
    margin-bottom: 0;
  }
  .trials .info-right p b {
    font-size: 16px;
  }
  .participate-sub-block {
    padding: 10px;
  }
  #Eligibility .section.mb40 {
    margin-bottom: 10px !important;
  }
  .contact-us h3 {
    font-size: 14px;
    font-weight: normal;
  }
  .center-margin {
    margin: 10px 10px 10px 0;
  }
  table.center-margin img {
    max-width: 90px;
  }
  .second-menu .nav-pills > li.active {
    border-bottom: 0px solid #00ced8;
    width: 100%;
    display: block;
  }
  .nav-pills > li {
    width: 100%;
    display: none;
  }
  .navbar-inverse .navbar-nav .open .dropdown-menu > li > a {
    color: #000;
    text-align: left;
    padding-left: 35px;
  }
  .removetopmargin {
    margin-top: 0px;
    margin-bottom: 10px;
  }
  .mobile-menu-close {
    display: none;
    position: absolute;
    top: 10px;
    right: 20px;
    cursor: pointer;
  }
  .img-center {
    max-width: 70px;
  }
  .trials .img-center {
    max-width: 65px;
  }
  .trials .img-center.mb20 {
    margin-bottom: 0 !important;
  }
  .full-image {
    max-width: 100%;
  }
  .navbar-collapse.collapse.in .mobile-menu-close {
    display: block;
  }
  .nav > li > a > img {
    max-width: 60px;
  }
  .nav.navbar-right > li > a > img {
    max-width: 11px;
  }
  .topmenu.nav > li > a {
    padding: 10px 10px;
    font-size: 10px;
  }
  .trial-status .codebreakbtn-home {
    width: 40% !important;
    max-width: 110px;
  }
  .trial-status h3 {
    line-height: 20px;
    margin-bottom: 0;
  }
  .codebreakbtn-home {
    padding: 5px;
  }
  .img-container {
    /* padding-top: 25px; */
  }
  .img-container .nmb img {
    width: 65px;
  }
  .roundsection {
    padding: 0px 0px 0px 0px;
  }
  .section {
    padding: 20px 0px 5px 0px;
  }
  #Study-Drugs .section {
    padding: 30px 0px 25px 0px;
  }
  #Study-Drugs .fz28.mb20 {
    margin-bottom: 1px !important;
  }
  .trials .centercontainer {
    display: block;
  }
  .trials .centercontainer .nlp {
    padding-left: 15px;
  }
  .trials .pull-right {
    float: none !important;
    text-align: center;
  }
  #Contact-us .pull-right img {
    margin: 0 auto;
  }
  #Study-Drugs p b {
    font-size: 20px;
    display: inline-block;
    padding-bottom: 5px;
  }
  sub {
    font-size: 10px;
  }
  #Overview .row > .fz28.mb20 {
    padding-left: 15px;
    padding-right: 15px;
  }
  #Overview .row.mb40 {
    margin-bottom: 0px !important;
  }
  .arrowbtn {
    position: absolute;
    left: 15px;
    top: 13px;
    font-size: 30px;
    color: #fff;
  }
  .topbutton {
    position: fixed;
    width: 45px;
    height: 40px;
    background-color: #288aab88;
    right: 15px;
    transition: all 0.4s;
  }
  .topbutton .arrowbtn img {
    width: 15px;
  }
  .topbtnSec {
    position: relative;
    height: 20px;
  }
  .trials .topbtnSec {
    margin-top: -50px;
  }
  .c-questions #PageStarts {
    padding-top: 85px;
  }
  .c-questions .topbtnSec {
    display: none;
  }
  .modal-header {
    padding: 5px 10px 5px 10px;
  }
  .modal-body {
    padding: 10px;
  }
  .modal-header .close .video-modal-close {
    margin-top: -2px;
    font-size: 20px;
  }
  .panel-title > a,
  .panel-title > a:active {
    padding: 12px;
    font-size: 14px;
  }
  .panel-body {
    padding: 0px 15px 10px 15px;
  }
  .centerdiv {
    margin-top: 15px;
  }
  .clinical-right-box p.heading {
    background-color: #167a9d;
    color: #ffffff;
    padding: 3px 5px;
    margin-bottom: 5px;
  }
  .clinical-right-box ul {
    padding: 0px 0 5px 30px !important;
  }
  .clinical-right-box {
    margin-bottom: 5% !important;
  }
  .clinical-right-box::before {
    border-width: 10px !important;
  }
  .timeline {
    padding-top: 10px;
  }
  .explore-heading {
    padding-bottom: 20px;
  }
  .topmenu.nav > li {
    text-align: center;
  }
  #Purpose .codebreakbtn {
    font-size: 14px;
  }
  .mutation p {
    margin-bottom: 10px;
  }
  .hero-image {
    background-image: url(../images/hero-image-home-mobile.png);
    height: auto;
    background-position: bottom;
    background-repeat: no-repeat;
    background-size: contain;
    position: relative;
    min-height: 750px;
  }
  .navbar {
    min-height: 50px;
  }
  .trial-status .data {
    font-size: 13px;
  }
  #PageStarts {
    padding-top: 70px;
  }
  .trial-status {
    padding: 10px 10px 20px;
  }
  .mtb30 {
    margin-bottom: 10px !important;
    margin-top: 10px !important;
  }
  .trial-status.first {
    margin-top: 0;
  }
  .hero-image-b {
    float: none !important;
    position: relative;
    bottom: 0;
    width: 100%;
  }
  footer p {
    padding-top: 10px;
    font-size: 10px;
    margin-bottom: 5px;
  }
  .header-logo {
    width: 160px;
    padding-top: 11px;
  }

  .home-page .header-logo {
    /* display: none; */
  }
  .code-breaktext h2 {
    font-size: 14px;
    font-weight: 600;
    line-height: 20px;
  }
  .code-breaktext img {
    max-width: 262px;
    width: 80%;
  }

  .code-breaktext {
    position: absolute;
    right: 0;
    top: 0;
    padding-bottom: 0px;
    padding-left: 0px;
    width: 100%;
    background-color: transparent;
    border: 0px solid #ffffff;
  }

  .codebreakbtn {
    width: 100%;
    margin-bottom: 5px;
  }

  .topmenu li {
    float: left;
  }
  .topmenu li:last-child a {
    padding-right: 0;
  }
  .codebreakbtn {
    font-size: 14px;
  }

  .navbar-nav {
    margin: 0 auto;
    float: left;
  }
  .in .navbar-nav {
    margin: 0 auto;
    float: left !important;
    padding-top: 10px;
  }
  .navbar-nav:last-child {
    float: right;
  }

  .navbar-inverse .navbar-toggle {
    border-color: transparent;
    z-index: 1111;
  }
  .logo-200 {
    padding-bottom: 0 !important;
  }
  .trials .trial-status,
  .trials .trial-status .col-sm-2 {
    padding-top: 0 !important;
  }

  .navbar-inverse .navbar-toggle .icon-bar {
    background-color: #24292c;
  }

  .navbar-toggle {
    margin-top: 10px;
    z-index: 100;
    position: absolute;
    top: -50px;
    right: -10px;
  }
  .navbar-toggle.collapsed .icon-bar + .icon-bar {
    margin-top: 5px;
  }
  .navbar-toggle .icon-bar + .icon-bar {
    margin-top: 1px;
  }
  .navbar-toggle.collapsed .icon-bar {
    display: block;
    width: 24px;
    height: 2px;
    border-radius: 1px;
  }
  .navbar-toggle .icon-bar {
    display: block;
    width: 19px;
    height: 4px;
    border-radius: 1px;
  }
  .navbar-toggle.collapsed {
    margin-top: 10px;
    z-index: 1111;
    position: absolute;
    top: -1px;
    right: -10px;
  }

  .main-menu.navbar-inverse .navbar-nav > li.active > a,
  .main-menu.navbar-inverse .navbar-nav > li.active > a {
    border-bottom: 0px solid #00ced8;
  }
  .main-menu.navbar-inverse .navbar-nav > li:focus > a,
  .main-menu.navbar-inverse .navbar-nav > li:hover > a {
    border-bottom: 0px solid #00ced8;
  }
  .main-menu .nav > li > a {
    padding: 0px 20px;
    font-size: 12px;
  }

  .printbtndiv {
    text-align: center;
  }

  .navbar-inverse .navbar-toggle:focus,
  .navbar-inverse .navbar-toggle:hover {
    background-color: transparent;
  }

  .navbar-brand {
    padding: 0px 15px;
  }

  .codebreak200btn {
    width: 100%;
    margin-bottom: 5px;
  }
  #Study-Drugs img {
    margin: 0 auto;
    max-width: 42px;
  }
  #Study-Drugs .col-xs-3 {
    padding-right: 0;
  }

  .image100widthonmobile {
    width: 100%;
  }
  footer {
    padding-bottom: 0px;
  }
  .footer-logo {
    margin: 0 auto;
  }

  .footer-link,
  footer a,
  footer a:hover,
  footer a:visited,
  footer p {
    padding: 1px 25px;
    font-size: 10px;
    clear: both;
    float: left;
    padding-left: 0px;
  }

  .cpwttext {
    text-align: center;
  }

  .footertext {
    padding-top: 0px;
  }
  .grey-background {
    /* margin-bottom: 5px; */
  }
  .desktop-only {
    display: none;
  }

  .mobile-only {
    display: block;
  }
  .mobiledropdown {
    width: 100%;
    border-radius: 0px;
    background-color: #fff;
    color: #000;
    border: 10px solid #95d82c;
    text-align: left;
    font-size: 14px;
    line-height: 14px;
  }
  .codebreak-101 .mobiledropdown {
    width: 100%;
    border-radius: 0px;
    background-color: #fff;
    color: #000;
    border: 10px solid #00ced8;
    text-align: left;
    font-size: 14px;
    line-height: 14px;
  }

  .mobiledropdown:hover,
  .mobiledropdown:active:focus {
    width: 100%;
    border-radius: 0px;
    background-color: #fff;
    color: #000;
    border: 10px solid #95d82c;
    text-align: left;
    font-size: 14px;
  }
  .mobiledropdown.active.focus,
  .mobiledropdown.active:focus,
  .mobiledropdown.active:hover,
  .mobiledropdown:active.focus,
  .mobiledropdown:active:focus,
  .mobiledropdown:active:hover,
  .open > .dropdown-toggle.mobiledropdown.focus,
  .open > .dropdown-toggle.mobiledropdown:focus,
  .open > .dropdown-toggle.mobiledropdown:hover {
    width: 100%;
    border-radius: 0px;
    background-color: #fff;
    color: #000;
    border: 10px solid #95d82c;
    text-align: left;
    font-size: 14px;
  }
  .dropdown-menu {
    width: 100%;
  }
  .mobiledropdown:before {
    font-family: "Glyphicons Halflings";
    content: "\e114";
    float: right;
    transition: all 0.5s;
    font-size: 10px;
    padding-top: 0px;
    color: #69adc4;
  }
  .trials #Purpose .mutation {
    float: left;
  }
  .codebreakbtnformobile {
    text-align: center;
  }

  .codebreakbtnformobile .codebreakbtn {
    width: 80%;
    margin-right: 0px;
  }
  .clinical-trial-image {
    width: 60%;
  }
  .CCT-heading {
    padding-top: 20px;
  }
  .navbar-inverse .navbar-brand {
    padding-left: 0;
    margin-left: -5px;
  }
  .cq-heading {
    padding-bottom: 15px;
  }
  .navbar-nav > li > a {
    padding-left: 0px;
  }
  .line {
    width: 325px;
    left: -67px;
    top: 190px;
  }
  /* .treatment-period {
			top: 196px;
		}
		.follow-up-period {
			top: 356px;
		} */
  .clinical-trial-period img.img-center {
    left: 0px;
    right: 0px;
    width: 38px !important;
    top: 23px;
  }
  .footnote-insidebox {
	padding-left: 16px;
    line-height: 1;
    padding-bottom: 10px;
  }
}

/* map css */

.site-lookup {
  width: 100%;
  position: relative;
  display: -webkit-box;
  display: -webkit-flex;
  display: -ms-flexbox;
  display: flex;
  -webkit-box-orient: vertical;
  -webkit-box-direction: reverse;
  -webkit-flex-direction: column-reverse;
  -ms-flex-direction: column-reverse;
  flex-direction: column-reverse;
  background: #008cad;
  -webkit-clip-path: inset(0 0 0 0 round 3px);
  clip-path: inset(0 0 0 0 round 3px);
}
.site-lookup__sidebar {
  padding: 2rem 2rem;
  min-height: 30rem;
}
.site-lookup__search {
  margin-bottom: 1rem;
}
input:not([type="radio"]):not([type="checkbox"]) {
  display: block;
  font: inherit;
  padding: 0.5rem 0.75rem;
  width: 100%;
  text-overflow: ellipsis;
  border: 1px solid #ded7d1;
  border-radius: 3px;
  margin-bottom: 0.5rem;
}
#google-location-search {
  padding-left: 1.5em;
  background: url(data:image/svg+xml;base64,PHN2ZyB2aWV3Qm94PSIwIDAgNTEgNjUuMiIgeG1sbnM9Imh0d…wxLDEsOS4xLTkuMUE5LjEzMzIyLDkuMTMzMjIsMCwwLDEsMjUuNSwzNC41WiIvPjwvc3ZnPg==)
    0.375em center no-repeat white;
  background-size: 0.782208588957055em 1em;
}
.site-lookup__list {
  max-height: 30rem;
  overflow: auto;
}
.site-lookup__list b {
  font-weight: 900;
}
.site-lookup__list > p,
.site-lookup__list li {
  /* border: 1px solid #ece8e5; */
  border-radius: 3px;
  padding: 1rem;
  background: white;
  margin-bottom: 2rem;
}
.site-lookup__list li {
  display: -webkit-box;
  display: -webkit-flex;
  display: -ms-flexbox;
  display: flex;
  -webkit-transition: all 0.125s linear;
  transition: all 0.125s linear;
  /* margin-right: 10px; */
}
.site-lookup__list .row {
  margin: 0;
}

.site-lookup__directions svg {
  width: 1.575em;
  height: 1.575em;
}
.site-lookup__map {
  width: 100%;
  min-height: 10rem;
  height: 80vw;
  position: relative;
}
.vue-map-container {
  position: relative;
}
.site-lookup__map .vue-map-container {
  width: 100%;
  height: 100%;
}
.site-lookup__list ul {
  padding-left: 0px;
}
.site-lookup__list ul li p {
  margin-bottom: 5px;
  line-height: 18px;
}
address {
  margin-bottom: 0px;
}
.miles,
.site-lookup__directions {
  font-size: 12px;
}
.site-lookup__directions {
  font-size: 12px;
  color: #288aab;
}

.centerdiv {
  margin: 0 auto;
}
table.centerdiv tbody tr td ul {
  text-align: left;
  padding-left: 20px;
}
.clinical-right-box {
  border: 2px solid #95d82c;
  margin-bottom: 11%;
  position: relative;
}
.clinical-101-box {
  border: 2px solid #00ced8;
  margin-bottom: 11%;
  position: relative;
}
.clinical-101-box::before {
  border-color: transparent #00ced8 transparent transparent !important;
}

.clinical-right-box::before {
  content: " ";
  position: absolute;
  top: 30px;
  right: 100%;
  margin-top: 0;
  border-width: 15px;
  border-style: solid;
  border-color: transparent #95d82c transparent transparent;
}
.clinical-right-box p.heading {
  background-color: #167a9d;
  color: #ffffff;
  padding: 5px 10px;
  margin-bottom: 10px;
}
.clinical-right-box ul {
  padding: 0px 0 15px 35px;
}

.font-normal {
	font-weight: 400;
}

@media (min-width: 768px) and (max-width: 1199px) {
  .trial-status .col-sm-1 {
    padding-right: 0px;
    padding-left: 0px;
    margin-left: -10px;
    min-width: 69px;
  }
}

@media (min-width: 768px) and (max-width: 991px) {
  #Purpose .codebreakbtn {
    font-size: 12px;
    width: 100%;
  }
}

@media screen and (min-width: 768px) {
  .modal-dialog {
    width: 500px;
  }
  #videoModal .modal-dialog {
    width: 60%;
  }
  #hcpmodal .modal-dialog {
    width: 427px;
  }
  .site-lookup {
    height: 75vh;
    max-height: 40em;
    -webkit-box-orient: horizontal;
    -webkit-box-direction: normal;
    -webkit-flex-direction: row;
    -ms-flex-direction: row;
    flex-direction: row;
  }

  .site-lookup__sidebar {
    display: -webkit-box;
    display: -webkit-flex;
    display: -ms-flexbox;
    display: flex;
    -webkit-box-orient: vertical;
    -webkit-box-direction: normal;
    -webkit-flex-direction: column;
    -ms-flex-direction: column;
    flex-direction: column;
    width: 45%;
    min-width: 20em;
    min-height: 100%;
  }

  .site-lookup__list {
    max-height: none;
  }

  .site-lookup__map {
    height: 100%;
  }

  .desktop-only {
    display: block;
  }

  .mobile-only {
    display: none;
  }

  .phase3-new {
    float: left;
    margin-top: 20px;
    width: 97%;
  }

  .phase3-Text {
    margin-top: 30px;
  }
  .clinical-trial-image {
    max-width: 100%;
  }
}

@media (max-width: 767px) {
  .line {
    width: 45%;
    left: -32%;
    top: 200px;
  }
}
@media (max-width: 670px) {
  .line {
    width: 50%;
    left: -12.5%;
    top: 180px;
  }
}
@media (max-width: 570px) {
  .line {
    width: 55%;
    left: -15%;
    top: 180px;
  }
}
@media (max-width: 500px) {
  .line {
    width: 60%;
    left: -17.5%;
    top: 180px;
  }
}
@media (max-width: 470px) {
  .line {
    width: 70%;
    left: -22.5%;
    top: 185px;
  }
}
@media (max-width: 450px) {
  .line {
    width: 80%;
    left: -28%;
    top: 200px;
  }
}
@media (max-width: 414px) {
  .line {
    width: 88%;
    left: -31.8%;
    top: 200px;
  }
}
@media (max-width: 390px) {
  .line {
    width: 98%;
    left: -36.5%;
    top: 226px;
  }
}
@media (max-width: 375px) {
  /* .follow-up-period {
			top: 355px;
		} */
}
@media (max-width: 320px) {
  /* .treatment-period {
			top: 212px;
		}
		.follow-up-period {
			top: 371px;
		} */
  .clinical-trial-period img.img-center {
    left: 0px;
    width: 38px !important;
    top: 20px;
  }
  .line {
    left: -52.5%;
    width: 415px;
    top: 258px;
  }
}
@media (max-width: 360px) {
  .hero-image {
    min-height: 750px;
  }
}

@media screen and (min-width: 440px) and (max-width: 500px) {
  .hero-image {
    min-height: 750px;
  }
}
@media screen and (min-width: 500px) and (max-width: 550px) {
  .hero-image {
    min-height: 775px;
  }
}
@media screen and (min-width: 551px) and (max-width: 600px) {
  .hero-image {
    min-height: 830px;
  }
}
@media screen and (min-width: 601px) and (max-width: 670px) {
  .hero-image {
    min-height: 880px;
  }
}
@media screen and (min-width: 671px) and (max-width: 740px) {
  .hero-image {
    min-height: 940px;
  }
}
@media screen and (min-width: 741px) and (max-width: 767px) {
  .hero-image {
    min-height: 990px;
  }
}

/* from map.html ----- */
.site-lookup__map {
  position: relative;
}

#map {
  height: 100%;
  width: 100%;
  overflow: auto;
  position: absolute;
}

#description {
  font-family: Roboto;
  font-size: 15px;
  font-weight: 300;
}

#infowindow-content .title {
  font-weight: bold;
}

#infowindow-content {
  display: none;
}

#map #infowindow-content {
  display: inline;
}

.pac-card {
  margin: 10px 10px 0 0;
  border-radius: 2px 0 0 2px;
  box-sizing: border-box;
  -moz-box-sizing: border-box;
  outline: none;
  box-shadow: 0 2px 6px rgba(0, 0, 0, 0.3);
  background-color: #fff;
  font-family: Roboto;
}

#pac-container {
  padding-bottom: 12px;
  margin-right: 12px;
}

.pac-controls {
  display: inline-block;
  padding: 5px 11px;
}

.pac-controls label {
  font-family: Roboto;
  font-size: 13px;
  font-weight: 300;
}

#pac-input {
  background-color: #fff;
  font-family: Roboto;
  font-size: 15px;
  font-weight: 300;
  padding: 0 11px 0 13px;
  text-overflow: ellipsis;
}

#pac-input:focus {
  border-color: #4d90fe;
}

#title {
  color: #fff;
  background-color: #4d90fe;
  font-size: 25px;
  font-weight: 500;
  padding: 6px 12px;
}

#target {
  width: 345px;
}

.site-lookup__list ul li:last-child {
  display: none;
}

.dropdown-menu {
  position: absolute;
  top: 100%;
  left: 0;
  z-index: 1000;
  display: none;
  float: left;
  min-width: 160px;
  padding: 5px 0;
  margin: 2px 0 0;
  font-size: 14px;
  text-align: left;
  list-style: none;
  background-color: #fff;
  background-clip: padding-box;
  border: 1px solid #ccc;
  border: 1px solid rgba(0, 0, 0, 0.15);
  border-radius: 4px;
  /* -webkit-box-shadow: 0 6px 12px rgba(0,0,0,.175); */
  box-shadow: 0 2px 6px rgba(0, 0, 0, 0.175);
}
.dropdown-menu > li > a {
  display: block;
  padding: 8px 11px;
  clear: both;
  font-weight: 400;
  line-height: 1.42857143;
  color: #333;
  font-size: 16px;
  background-color: #F2F8FA;  
  width: auto;
  white-space: inherit !important;
  text-align: left;
  min-width: 209px;
}
.dropdown-menu > li > a:hover {
  color: #FFFFFF;
  background-color: #288AAB;
}
.padding-right {
  padding-right: 124px;
}

@media screen and (min-width: 768px) and (max-width: 991px) {
  .dropdown-menu > li > a {
    min-width: 0px;
  }
  .padding-right {
    padding-right: 21px;
  }
}
@media only screen and (min-width: 1024px) and (max-height: 1366px) and (orientation: portrait) and (-webkit-min-device-pixel-ratio: 1.5) {
  .padding-right {
    padding-right: 74px;
  }
}
@media only screen and (min-width: 360px) and (max-height: 568px) and (orientation: portrait) and (-webkit-min-device-pixel-ratio: 1.5) {
  .padding-right {
    padding-right: 6px !important;
  }
}
@media only screen and (min-width: 375px) and (max-height: 667px) and (orientation: portrait) and (-webkit-min-device-pixel-ratio: 1.5) {
  .padding-right {
    padding-right: 37px !important;
  }
}
@media only screen and (min-width: 411px) and (max-height: 823px) and (orientation: portrait) and (-webkit-min-device-pixel-ratio: 1.5) {
  .padding-right {
    padding-right: 56px !important;
  }
}
@media only screen and (min-width: 360px) and (max-height: 640px) and (orientation: portrait) and (-webkit-min-device-pixel-ratio: 1.5) {
  .padding-right {
    padding-right: 26px !important;
  }
}
@media only screen and (min-width: 375px) and (max-height: 812px) and (orientation: portrait) and (-webkit-min-device-pixel-ratio: 1.5) {
  .padding-right {
    padding-right: 35px !important;
  }
}
.modal-footer {
  padding: 15px;
  text-align: right;
  border-top: none !important;
  background-color: #fff;
}
.btn-default {
  background-color: transparent;
  color: #288aab;
  font-size: 20px;
  border: 1px solid #00ced8;
  margin: 10px 0;
  -webkit-transition: all 1s;
  transition: all 1s;
  padding: 10px 35px;
  float: left;
}
.btn-default:hover {
  background-color: rgba(22, 122, 157, 0.1);
  color: #288aab;
  -webkit-transition: all 1s;
  transition: all 1s;
}
.cookie-modal-header {
  background-color: #288aab;
  padding: 0px;
}
@media (max-width: 767px) {
  .btn-default {
    font-size: 14px;
  }
}




/* .dropdown-menu {
	margin-top: 8px !important;
} */
.dropdown-menu {
  top: 60px;
  z-index: 1000;
  max-width:304px;
  padding: 0 0;
  list-style: none;
  background-color: transparent;
  border: 1px solid #ccc;
  border: 0px solid rgba(0, 0, 0, 0);
  border-radius: 4px;
  -webkit-box-shadow: 0 6px 12px rgba(0, 0, 0, 0.175);
  box-shadow: 0 6px 12px rgba(0, 0, 0, 0.175);
  text-align: center;
  position: absolute;
  background-color: #ffffff;
  margin-top: 10px !important;
  overflow: hidden;
}

.videobutton:before {
  content: "";
  width: 0;
  height: 0;
  border-style: solid;
  border-width: 5px 0 5px 8px;
  border-top: 5px solid transparent !important;
  border-bottom: 5px solid transparent !important;
  border-left: 8px solid #288aab !important;
  display: inline-block;
  /* margin-left: -2px; */
  top: -2px;
  padding-left: 10px;
  position: relative;
}
.video-modal-header {
  background-color: #ffffff;
  padding: 0px 0px 0px 0px;
  border-bottom: none !important;
}
.video-modal-close {
  float: right;
  font-size: 26px;
  font-weight: 700;
  line-height: 1;
  color: #000;
  text-shadow: 0 1px 0 #fff;
}
#video-modal-body {
  background-color: #fff;
  padding: 0 !important;
}
#videoModal button.btn.btn-default {
  position: absolute;
  right: 0;
  z-index: 5;
  color: white;
  margin: 2px;
}




/* New CSS Added HERE */
.breadcrumb{background-color: transparent;margin-bottom: 0;padding-top: 21px;padding-left: 0;}
.breadcrumb p{margin: 0;}
.breadcrumb p span{color: #288AAB;}
.codebreak-header-section{margin-bottom: 23px;}
.codebreak-header-section p{vertical-align: top;display: inline-block;margin-bottom: 0;}
.codebreak-header-section h2{vertical-align: middle;display: inline-block;font-size: 19px;line-height: 20px;}
.codebreak-header-section span{
  font-size: 41px;
  margin-left: -20px;
}
.m-hide{
  display: none;
}
.m-show{
  display: block;
}
.pad-0{padding: 0;}

@media (min-width: 768px) {
  .d-show{
    display: block;
  }
  .d-hide{
    display: none;
  }
  .codebreak-header-section h2{vertical-align: top;font-size: 23px;line-height: 49px;}
}
@media (min-width: 992px) {
  .codebreak-header-section h2{font-size: 41px;line-height: 49px;margin-top: -8px;}
}

.enrollbtn {
  background-color: #288AAB;
  border: 1px solid #00CED8;
  margin-top: 6px;
  margin-bottom: 6.5px;
  color: #ffffff;
  font-size: 16px;
  margin-right: 16px;
  -webkit-transition: all 1s;
  transition: all 1s;
}
.enrollbtn:hover, .enrollbtn:hover:focus {
  background-color: rgba(22, 122, 157, 0.1);
  color: #288aab;
}

.enrollbtn:focus{
  color: #ffffff;
}
#PageStarts #trails .section{
  padding-top: 15px;
}

.step-image-box img{
  margin-top: 10px;
  margin-bottom: 25px;
}
.step-image-box p{
  clear: both;
  margin-top: 0;
  margin-bottom: 14px;
}
.step-image-box ul{
  padding-left: 15px;
}

.border-color-201 {
  border-color: #95D82C !important;
}

.border-201{
  border-color: #95D82C !important;
}

.border-color-201::before {
  border-color: transparent #95D82C transparent transparent !important;
}

.codebreak-300 .second-menu .nav-pills > li.active > a{
  border-color: #FFC602 !important;
}

.border-color-301 {
  border-color: #FFC602 !important;
}

.border-301{
  border-color: #FFC602 !important;
}

.border-color-301::before {
  border-color: transparent #FFC602 transparent transparent !important;
}
.mobile-enroll-btn{margin-top: 15px;}
.mobile-enroll-btn .enrollbtn{
  width: 274px;
  margin-right: 0;
  /* margin-bottom: 2+5px; */
}

.intro-btn .enroll-home{
  padding: 8px 16px;
  margin: 10px 0 10px 0;
  font-size: 14px;
  border: 1px solid #00ced8;
  margin-right: 10px !important;
  display: inline-block;
  vertical-align: middle;
}
.intro-btn .enroll-home:focus{
  color: #ffffff;
}
.intro-btn .codebreakbtn-home{
  display: inline-block;
  vertical-align: middle;
  margin: 10px 0 10px 0 !important;
  margin-right: 10px !important;
  padding: 8px 15px !important;
  width: auto; 
}
.intro-btn .codebreakbtn-home:nth-last-of-type(1){margin-right: 0 !important;}

.sub_text{
  font-size: 14px;
}

.big-font{
  font-size: 20px;
  line-height: 32px;
}
@media (min-width: 992px) {
  .mobile-enroll-btn{display: none;}
  .intro-btn .enroll-home{
    padding: 10px 35px !important;
    font-size: 20px;
    margin: 15px 0 20px 0 !important;
    margin-right: 20px !important;
  }
  .intro-btn .codebreakbtn-home{
    padding: 10px 35px !important;
    font-size: 18px;
    margin: 15px 0 20px 0 !important;
    margin-right: 20px !important;
  }
  .intro-btn .codebreakbtn-home:nth-last-of-type(1){margin-right: 0 !important;}
}
.modal-content-box{margin-bottom: 20px;}
@media (min-width: 768px) {
  .big-font{
    font-size: 28px;
    margin: 20px 0;
  }
  .modal-content-box p{
    margin-bottom: 5px;
  }
}
.arrow{position: relative;display: inline-block;vertical-align: middle;}
.arrow::before{
  position: absolute;
  bottom: -2px;
  right: -8px;
  height: 6px;
  width: 1.5px;
  content: '';
  transform: rotate(-45deg);
  background-color: #000000;
}
.arrow::after{
  position: absolute;
  bottom: -2px;
  right: -12px;
  height: 6px;
  width: 1.5px;
  content: '';
  transform: rotate(45deg);
  background-color: #000000;
}
@media (min-width: 1200px) {
  .main-menu .navbar-nav > li{
    padding: 36px 45px 0 0;
  }
}

.codebreak-300 .second-menu .nav-pills > li:hover > a{
  border-color: #FFC602;
  color: #FFC602;
}

.main-menu.navbar-inverse .navbar-nav li a:hover .arrow::after,
.main-menu.navbar-inverse .navbar-nav li a:hover .arrow::before,
.main-menu.navbar-inverse .navbar-nav li a:focus .arrow::after,
.main-menu.navbar-inverse .navbar-nav li a:focus .arrow::before{
  background-color: #00ced8 !important;
}

@media (max-width: 992px) {
  .navbar-nav .open .dropdown-menu {
    position: static;
    float: none;
    width: auto;
    margin-top: 0;
    background-color: transparent;
    border: 0;
    -webkit-box-shadow: none;
    box-shadow: none;
    margin-top: 0 !important;
  }
  .dropdown-menu > li > a{
    background-color: transparent;
    padding-left: 35px;
  }
  .main-menu .nav > li > a {
    padding: 0px 20px;
  }
  .dropdown.show .dropdown-menu.show{
    display: none !important;
  }
  .dropdown.show.open .dropdown-menu.show{
    display: block !important;
  }
}